HUGE! Today, 100 years later, it is being studied for a variety of applications and treatments . According to a comment on a doctor video [2] Severe side effects may include low blood pressure, decreased level of consciousness, kidney problems, and low blood cell levels. Thankfully God has not left them and us comfortless, there is an antidote, Suramin, that Dr. Judy Mikovits and others speak about in this article, available in Pine Needle Tea you can make yourself. Sartor, Oliver, Catherine A. McLellan, Charles E. Myers, and M. M. Borner. These are proving to be beneficial for people who have taken the jab, or those who come in contain with injected people and find they are experiencing bad symptoms. [8][9] It is considered first-line treatment for Trypanosoma brucei rhodesiense, and second-line treatment for early-stage Trypanosoma brucei gambiense, where pentamidine is recommended as first line. Coffey Jr, Robert J., Edward B. Leof, Gary D. Shipley, and Harold L. Moses. And yes my neighbors thought I was crazy when they saw me collecting them. antiviral activities [24], and most of these are generally of low toxicity, cheap and 2! Quercetin is an antioxidant found naturally in . I am a mother. Suramin may cause serious side effects. The approved pediatric drug suramin identified as a clinical candidate for the treatment of EV71 infection-suramin inhibits EV71 infection in vitro and in vivo. (2020). Due to its anti-inflammatory properties, turmericspecifically curcumin, the main active ingredientmay be one of the top natural remedies showing promise for treatment and management of autism symptoms. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. It loves the cold, the colder the better. A lawn treated with Roundup would also have no grass, as well as no dandelions, no anything. Within minutes, behavior returned to normal. The Eastern White Pine (. It prevents the association of heteromeric G proteins and therefore the receptors guanine exchange functionality (GEF). [1] Specifically, it is used for treatment of first-stage African trypanosomiasis caused by Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense without involvement of central nervous system. [9], It has been used in the treatment of river blindness (onchocerciasis). XXIV. Descriptions. As you dig really deep, you may be surprised what youll dig up. Prunella vulgaris, widely distributed in China, Europe, 5! We administered suramin, an anti-parasitic drug and reverse transcriptase inhibitor, to 15 patients with metastatic cancer. Graded amounts of extracellular ATP (eATP) are released from cells in proportion to stress. Research is already being hurriedly done in that direction in the hope that many lives can be saved and much severe illness avoided. '+arguments[1].video:'')+"/?url="+encodeURIComponent(location.href)+"&args="+encodeURIComponent(JSON.stringify([].slice.apply(arguments))),e.parentNode.insertBefore(l,e)}})}(window, document, "script", "Rumble"); Rumble("play", {"video":"vh8kgv","div":"rumble_vh8kgv"}); Let food be thy medicine and medicine be thy food. ~Hippocrates, So do not fear, for I am with you; do not be dismayed, for I am your God. Thank you!). [17]:378379[18], It is also used as a research reagent to inhibit the activation of heterotrimeric G proteins in a variety of GPCRs with varying potency. Having said that, we can do a lot more about it than simply sitting around and waiting to see who is harmed or dies. Gourley, P.L. interesting! PubChem . The same protocol is very useful to protect those concerned with the spike protein transmission FROM those whove been injected. Suramin and trypan blue were detected using scheduled multiple reaction monitoring (MRM) with a dwell time of 30 ms in negative mode and retention time window of 7.5-8.5 min for suramin and 8.4 . Since a lowered pHe is also known to enhance agonist activity at P2X receptors on sensory neurones containing P2X2 transcripts, the sensitization by metabolic acidosis of native P2X receptors containing P2X2 subunits may have a significant effect on purinergic cell-to-cell signalling. Its a remedy used a very long time ago. Bumping this to see if anyone's benefited from high dose Kudzu, Good question, I don't have a good answer, though someone with more scientific knowledge than me could probably calculate it using the paper cited above, I'd be remiss if I didn't post this Kudzu precaution literature. These pannexin channel blockers will likely be synergistic with anti-purinergic drugs in helping to reset, reboot, and support the completion of the healing cycle when it becomes stuck in any of the stages of the CDR. Interesting info Martin! Stresses of all kinds are translated by the cell into graded eATP release. I have never actually taken turpentine it makes me think of the turps used to wash out paint brushes and makes me gag at the thought but I have watched a BioChemist share how to make your own and how to take it. [12], Suramin is not orally bioavailable and must be given intravenously. 9. Antiviral Research 121, 39-46. She was healthy and lived a long life taking this faithfully. ?? 9. Being jabbed with strange substances and experiencing shedding from those individuals has become a reality in this world we live in. JavaScript is disabled. 14.Stein, C. A., R. V. LaRocca, R. Thomas, N. McAtee, and Charles E. Myers. 100 Years of Suramin. Personally, 40mg of Emodin a day for the past three weeks has not produced great results. I dont know but I do know that God will provide. what about plavix? And this gem of a video by Judy Mikovits. A small study found that a 100-year-old drug called suramin, which is used to treat African sleeping sickness, showed promising results for treating autism spectrum disorder (ASD) symptoms in . When he had an ME attack (as he called them), he would boil a load of soya beans, which he claimed made him feel much better. I've come across two over the counter supplements that inhibit the same purinergic receptors. If you continue to use this site we will assume that you are happy with it. He knew they would tamper with our food supply, robbing it of all the necessary nutrients for life and health. 6 Natural Alternatives to Ivermectin with Herbs. Antiviral research 7, no. Hen, L. et al. By the way, enterovirus can cause gastritis, as well as being linked to ME/CFS. $8.99 to $12.75. For research, treatments, and personal stories regarding Chronic Fatigue Syndrome (CFS)/Myalgic Encephalomyelitis (ME). 5. A strange star shaped spice that has a really nice flavour. Enlighten yourself - become aware of what is pulling your health down on a daily basis and what to do about it! Ive currently run out of it but once I source a good organic variety somewhere, Im going to infuse it and make up a batch of tea to store in the fridge can then drink it anytime without having to go through the process of making it. These days I get to enjoy Fennel whenever I so choose, and thats often. Common side effects include nausea, vomiting, diarrhea, headache, skin tingling, and weakness. OK, last one, because I'm still trying to understand it. Suramin is used in the treatment of African sleeping sickness (African trypanosomiasis) and river blindness (onchocerciasis), infections caused by parasites. I believe that most of the fake foods will be removed and people will learn how to eat food they were designed to eat. An extremely good read Fed Up by Sue Dengate. And while parents can't yet turn to their doctors to ask for this . A: Generally acceptable. especially valuable as potential new sources for rapid responses against the ongoing 4! SMALL SURAMIN STUDY. I do seek scientific confirmation of the safety and effectiveness of the herbs and remedies I use. 21. Any natural medicine with 0.01% of these deaths and side effects would have been pulled from the market immediately . They do change our DNA in the sense that they take it back to how it was when we were a baby. These people invite evil spirits to come into them and tell the HS He must depart! This information isn't meant to treat, cure or prevent any disease. [23], Suramin has been studied in a mouse model of autism and in a small phase I/II human trial. Homeopathic remedies have been praised by advocates for use against viruses and routine ailments. Mayan's Secret Organic Black Cumin Seed Oil. Alcohol, well Ethanol, is not a p2x antagonist. y puede cancelar su suscripcin en cualquier momento. ", 21. Suramin is a potent inhibitor of sirtuins: SirT1 (IC50=297 nM), SirT2 (IC50=1.15 M), and SirT5 (IC50=22 M). Myers, Charles, Michael Cooper, Cy Stein, Renato LaRocca, M. M. Walther, Gary Weiss, Peter Choyke, Nancy Dawson, Seth Steinberg, and Margaret M. Uhrich. Im worried about the mark of the evil one. "Suramin rapidly alters cellular tyrosine phosphorylation in prostate cancer cell lines. When I had an organic yard full of dandelion flowers I would harvest the flowers every morning, saut them and cook them into my scrambled eggs. 20. We were lucky that suramin is a non-selective inhibitor of most of the known types of purinergic receptors. Create an account to follow your favorite communities and start taking part in conversations. As follows: The Antidote to the Contagion The natural alternative of Suramin - and the original compound is found in Eastern White Pine (pinus strobus) needles. "Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin." Coffey Jr, Robert J., Edward B. Leof, Gary D. Shipley, and Harold L. Moses. Most importantly the mysterious seizure-like episode has disappeared. 17 (1987): 4694-4698. Xu, H. Eric, Wanchao Yin, Xiaodong Luan, Zhihai Li, Leike Zhang, Ziwei Zhou, Minqi Gao et al. You can obtain enough from pine needle tea (pine, spruce, cedar and fir) . This has the effect of blocking downstream G protein mediated signaling of various GPCR proteins including rhodopsin, the A1 adenosine receptor, the D2 receptor,[19] the P2 receptor,[20][21] and ryanodine receptors. Dr. Daniels has now been using this and has no issues and I have been using it also. The intracellular application of 100 mM ethanol did not affect the inhibition of current by 100 mM extracellular ethanol, suggesting that the alcohol inhibition of ATP-gated ion channel function involves the extracellular domain of the receptor. Virol J 13, 149 (2016). You must log in or register to reply here. Turn your volume down inititially. Here he talks about suramin, which Dr Judy mentioned. Several P2Y12 inhibitors are approved to treat heart disease, but other purinergic receptors are likely to be more important in ASD. For alcohols with a molecular volume of < or = 42.2 ml/mol, potency for inhibiting ATP-activated current was correlated with lipid solubility (order of potency: 1-propanol = trifluoroethanol > monochloroethanol > ethanol > methanol). Tea made from pine cones is a real treasure of useful substances. One day I just may try that. Albulescu, I.C., van Hoolwerff, M., Wolters, L.A., Bottaro, E., Nastruzzi, C., Yang, S.C., Tsay, S.-C., Hwu, J.R., Snijder, E.J., and van Hemert, M.J. (2015). Suramin has been used for years to combat African sleeping sickness and river blindness but it has also been found beneficial in slowing the . It happened with the first a few days and soon I realized he started to sleep very well without Melatonin. Yin, W. et al. Choose what fits your situation best. PloS one 9, e91765-e91765. Hi, thanks for this information. so i do wonder what the one is behind Suramin. I do you a concern about the med beds and whether the DNA is actually being reconstructed our is it possible that our DNA is being changed-much the way the jab is changed and damaged. 1. Food Shortage Coming Soon, County Returns $1.2M NIH Funds & Confirms Vaxx is a Bioweapon, Protect Babies Thru Adults From Dioxin Toxicity w/ Adequate Vit C, DETOX Dioxin Air & Soil Exposure w/ Broccoli Sprouts For Pennies, Natures Penicillin: For Pneumonia, Earache, Flu, Bronchitis & More. Some of the other P2X7 and P2Y2 inhibiting compounds listed at the bottom of. The autistic boys were randomized to receive either one intravenous infusion of low-dose suramin or a placebo infusion. I will continue to research it, but at this time Im not convinced. The all natural form of suramin might be licorice root, NAC,vitamin C , green tea. POLG Mutations Associated with Alpers Syndrome and Mitochondrial DNA Depletion. By accessing or using this website, you agree to abide by the Terms of Service, Full Disclaimer, Privacy Policy, Affiliate Disclosure, and Comment Policy. I did feel better with better health after I drank it myself. No medical research confirms this yet, but people have been using suramin for autism and as a powerful antiviral. The first shoots used to be used as a spring tonic many years ago. Unfortunately, the importance of ATP and related metabolites in regulating the symptoms of disease and the stages of the healing cycle has only recently been recognized. B-complex vitamins: The "complex" part is important. (3) This study also says suramin doesn't work well on p2x4. "Suramin: a novel growth factor antagonist with activity in hormone-refractory metastatic prostate cancer. 2. Still, I do drink it occasionally. It's the first time we've been so close to having a drug that can potentially treat ASD symptoms. 49 natural alternative to Ivermectin, due to its rapid degradation, low toxicity to mammals 16, and 50 effectiveness in controlling nematodes and ticks 17,18. I'm not too concerned about Il-6 being a problem in CFS but I've thought about that receptor a bit. (2014). ", 16.Spigelman, Zachary, Amy Dowers, Susan Kennedy, Dennis DiSorbo, Michael O'Brien, Ronald Barr, and Ronald McCaffrey. [10], Rare side effects include hypersensitivity reactions causing difficulty breathing. Just a point of clarification. "Studies on antitumor effects of pine needles, Pinus densiflora Sieb. Im so thankful that we are entering into a whole new era. It is illegal to use suramin in humans for any purpose in the US except in FDA-approved clinical trials. But raw milk just doesnt last as long in the fridge, so keep most of it in the freezer and only bring out one serving at a time into the fridge the night before using. Suramin is a 100-year-old drug developed to treat African sleeping sickness and river blindness. "Suramin" is the antidote to the bioweapons and transmission. They were ahead of their time back then. (2020). Even the first 5 minutes are explosively informative. However, a small, randomized clinical trial conducted by Robert Naviaux, MD, PhD, professor of medicine, pediatrics and pathology, and colleagues at University of . In summary, a lowered pHe enhanced the activity of all agonists at P2X2 receptors but, with the exception of suramin, not antagonists. The first thing we noticed was the improvement in his articulation. 22. ", 9. Maca Root 8050mg Per Caps, 4 Months' Supply Supports Reproductive Health Natural. Suramin is used in the treatment of African sleeping sickness (African trypanosomiasis) and river blindness (onchocerciasis), infections caused by parasites. For Candle Soap Incense Making Burners Scented Oils Bulk Lot. Salgado-Benvindo, C. et al. The differences are about 20% higher. So head over today and like, share and download a few episodes! [11], Less common side effects include extreme fatigue, ulcers in the mouth, and painful tender glands in the neck, armpits and groin. Suramin was shown to be safe and effective in three preclinical models of ASD9-11 and a small human clinical trial1 in peer-reviewed papers published between 2013-2017. Our research is aimed at discovering a completely new way to think about the cause and treatment of autism and dozens of other complex chronic disorders. Suramin is just the first in a new class of drugs that will be synthesized to help regulate purinergic signaling. Suramin successfully improved all the core symptoms of ASD and the metabolic and GI abnormalities in both animal models and a small human clinical trial. Suramin (as mentioned by Dr Judy Mikovits, PhD) and Shikimic acid are both found within the needles of the common pine tree. [16], Suramin was first made by the chemists Oskar Dressel, Richard Kothe and Bernhard Heymann at Bayer AG laboratories in Elberfeld, after research on a series of urea-like compounds. 3 (2006): 899-906, 18.https://pubchem.ncbi.nlm.nih.gov/compound/Suramin-sodium. Suramin may cause severe hypersensitivity reactions (shock and loss of consciousness). The respective distribution of glycosome volumes and for cells treated for 72 h with suramin is shown as a bar graph. El PDF llegar a su buzn de entrada! 6 (1992): 881-889. Journal of ethnopharmacology 35, no. 17.Kathir, Karuppanan Muthusamy, Thallapuranam Krishnaswamy S. Kumar, and Chin Yu. Its a 100 year old essential medicine, a WHO essential medicine for African Sleeping Sickness. a cup and enjoy! It is a growth factor antagonist for palliative treatment in hormone-refractory prostate cancer and hormone-responsive metastatic prostate cancer.. Purpose. [22], Suramin was studied as a possible treatment for prostate cancer in a clinical trial. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties. Could you please attach links if possible. National Library of Medicine. A polyanionic compound with an unknown mechanism of action. As we know, oil and water do not mix, but this mixes the oil into the water long enough for me to have a drink. I tried it for the lipid modulating properties and have seen some improvement in various serum lipid ratios (though of course I don't know that this is specifically attributable to the Sytrinol). Another thing I would recommend is that you visit a naturopath. Structural Basis For Repurposing A 100-Years-Old Drug Suramin For Treating COVID-19. (5) $11.00 New. Thank you Lizzy for sharing this with us so much appreciated. Biochemistry 45, no. 3 (1985): 265-273. Though, the other day I did hear someone saying that the bark is even more powerful than the needles so maybe thats something you can follow through on. ME/CFS is a multi-systemic neurological disease, distinct from chronic fatigue as a symptom. You must realise too that the medbeds are for good and not evil. However, even better than the medication known as Suramin, and one that does not produce all the adverse side effects that come with pharmaceutical drugs, perhaps Pine Needle Oil may serve as a natural silver bullet. "Suramin binds to plateletderived growth factor and inhibits its biological activity." One important way that stress-triggered eATP is released occurs through pannexin 1 containing channels in the cell membrane. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website. Regarding our own experiment with natural antipurinergic therapy, we've been trialing Kudzu for the past three weeks and the outcome has been pretty impressive. 7. (2017) conducted a trial that studied the impact of a single dose of suramin in children with autism and compared their result to a group of children who received the placebo drug (Saline). It is considered a ryanodine agent . It is the treatment of choice for sleeping sickness without central nervous system involvement. The boys were extensively monitored in the following 6 weeks for suramin blood levels, a panel of blood chemistry, adverse effects and autism-related traits. There is a lot of research available on the internet about this. "Suramin inhibition of growth factor receptor binding and mitogenicity in AKR2B cells." Betsholtz, Christer, Ann Johnsson, Carl-Henrik Heldin, and Bengt Westermark. Jacques Update:Facebook and social media platforms are cracking down on Conservative/holistic health content. This site is NOT intended to be a substitute for a healthcare providers consultation: NEVER DISREGARD MEDICAL ADVICE OR DELAY IN SEEKING IT BECAUSE OF SOMETHING YOU HAVE SEEN ON THIS SITE. Suramin was first synthesized by Bayer chemists in Germany in 1916. [3] It is given by injection into a vein. Looks like part of my theories is debunkable - one of the authors did think to check IL-6 and IL-6R before and after exercise in CFS patients (good on him) and found no differences between them and the controls, although he did find "F(2)-isoprostanes were higher (P<0.05) in CFS patients at rest and this difference persisted immediately and 24 h post-exercise." 1 (1987): 1-10. Do you think that Rheum Palmatum is the richest plant? I haven't seen night awake or silly giggling in the middle of the night since he started Kudzu. Antimicrob Agents Chemother 64(2020). Suramin is a potent inhibitor of Chikungunya and Ebola virus cell entry. I have bought this before for myself just for good health. Or can you eat them raw or just cooked? Its considered almost a pest in New Zealand as its everywhere. It is still early to say but maybe this will enter the top three interventions. & Naviaux, R.K. Optical phenotyping of human mitochondria in a biocavity laser. I love the fact that you are speaking from what you yourself did excellent! If you have any healthcare-related concerns, please call or see your physician or other qualified healthcare provider. He truly is speaking much in these days. UPDATE 8/1: Now graphene oxide has been confirmed with irrefutable documentation by former Pfizer employee whistleblower and current analyst for the pharmaceutical and medical device industrieshere. I have always loved the taste of Fennel yum! Everything from high blood pressure, to psychological trauma, chemotherapy, surgery, toxin or pesticide exposure, stroke or heart attacks cause eATP to be released. Some Amish farms sell and ship this. Reddit and its partners use cookies and similar technologies to provide you with a better experience. Its not a matter of if, its a matter of when. We loved pickled everything, sour the better. A small, FDA-approved phase 1 clinical trial in 2017 tested suramin's effect on certain "core" autism symptoms in five boys, as compared with five boys given a placebo. Dr. Jennifer Danials Turpentine and sugar was a bit of a story about a Grand Mother had done for years. Quoting from our 2017 publication,Like many intravenous drugs, when administered improperly by untrained personnel, at the wrong dose and schedule, without careful measurement of drug levels and monitoring for toxicity, suramin can cause harm. "After the single dose, it was almost like a roadblock had been released," he said. Though it has been investigated for other diseases, including cancer, it is not approved for any therapeutic use in the United States. Careful clinical trials will be needed over several years at several sites to learn how to use low-dose suramin safely in autism, and to identify drugdrug interactions and rare side effects that cannot currently be predicted. I have heard of a study at UCSD using Suramin to treat autism. Is there one specific product you would recommend? Therefore only 5 boys received suramin by infusion. Unfortunately, the lawns that do not have any yellow flowers have often been treated with RoundUp which is about the very worst thing you can do. "Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes. It is not found in pine needles and cannot be found in any herbal teas. The research is promising and the findings are backed up by similar studies. C: Use with caution if benefits outweigh risks. Garlic is a natural remedy which cleans your blood and body of toxins. It was a remedy taken before flu season. Kudzu is one although it is not as potent. Natural products still play an important role in therapy: between 1981 and 2006, 1,184 new drugs were registered of which 28% were natural products or their derivatives. Do we know the complete answer? Thank you, Jo . to protect from transmission from the V and to help those who took the V, We are covering everything from vaccines, parenting topics, alternative medicine, and. Nothing present here is intended to diagnose or treat any disease, and there are no supplements or products offered for sale in relation to this information. Press question mark to learn the rest of the keyboard shortcuts. However, despite increased lipid solubility, alcohols with a molecular volume of > or = 46.1 ml/mol (1-butanol, 1-pentanol, trichloroethanol, and dichloroethanol) were without effect on the ATP-activated current. [10] Other rare side effects include symptoms of liver dysfunction such as tenderness in upper abdomen, jaundice in eyes and skin, unusual bleeding or bruising. Disclaimer: The information presented in this article and podcast are for informational purposes only. Albulescu, I.C., Kovacikova, K., Tas, A., Snijder, E.J., and van Hemert, M.J. (2017). Ivermectin is a medication widely used in low- and middle-income . The Neem's active substance, azadirachtin, 51 a tetranortriterpenoid plant limonoid, is a potent insect feeding deterrent and, if consumed, 52 causes . Kudzu has been shown to be an agonist of the P2X7 receptor (. Pine Trees are widely available throughout the world and make an amazing tea high in vitamin C and A. However. [6] In the United States it can be acquired from the Centers for Disease Control (CDC). The study participants in question used 300 milligrams (mg) each day. "Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes." We are covering everything from vaccines, parenting topics, alternative medicine, and I just gave my testimony of past abortion. The purpose of this website is to promote broad consumer understanding and knowledge of various health topics. Trypan blue is derived from toluidine, that is, any of several isomeric bases, C14H16N2, derived from, The inhibitory effect of suramin from pine needles on the coronavirus spike protein, Zika and Chikungunya, Making pine needle tea is easy, and only requires fresh, young pine needles and hot water. This compound is known to inhibit the binding of growth factors (eg, epidermal growth factor [EGF], platelet-derived growth factor [PDGF], tumor growth factor-beta [TGF-beta]) to their receptors and thus antagonize the ability of these factors to stimulate growth of tumor . Suramin is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor.Suramin efficiently . Proceedings of the National Academy of Sciences 83, no. Two hours later, wanted to do class with me and did her toughest one, reading. Researchers Studying Century-Old Drug in Potential New Approach to Autism. Fragrance Oil 4 oz. Yes, it can certainly be found naturally. Suramin can be found in trees, plants and spices which may be growing even in your front lawn! "Antimicrobial activity of the essential oil of young pine shoots (Picea abies L.)." We now have evidence of the injections containing: mRNA, spike protein, graphene oxide, and highly toxic SM-102, and other potentially toxic substances. "Suramin: a novel growth factor antagonist with activity in hormone-refractory metastatic prostate cancer." We have two sons with Autism and are verbal but are not using full sentences accompanied by the usual jumping, head and hand movements and jumping. Cat's claw, hailing from a woody vine in the Amazon rainforest, is another herb with spectacular antiviral properties. . Dont forget to also check what else you need to do to build your immune system strong it will be more than worth it in the end. I am not a total fan of the taste but absolutely love the aroma of it before the water hits it. Ive seen some dandelions in a vegetable patch that were so big I could hardly believe how big they were. You cannot continue to consume fake foods, day in and day out, and for your body not to react to it. 12.Cheng, B., Gao, F., Maissy, E., and Xu, P. (2019). Once all the needles have sunk to the bottom and the tea has . Suramin further decreases the activities of a large number of enzymes involved in DNA and RNA synthesis and modification: DNA polymerases (103, 104), RNA polymerases (103, 105, 106), reverse transcriptase (18, 103), telomerase (67), and enzymes involved in winding/ unwinding of DNA (107, 108) are inhibited by suramin, as well as histone- and chromatin-modifying enzymes like chromobox proteins . The Journal of clinical investigation 90, no. Suramin does not cross the bloo Treatment of late-stage human African trypanosomiasis is complicated by the presence of trypanosomes within the central nervous system (CNS). And I get the best of both worlds. (See protocol below). Other P2X receptors are inhibited by H+ ions, so that acidic conditions greatly reduce the potency of extracellular ATP. The drug is still sold by Bayer under the brand name Germanin. ", 20. When suramin was first introduced for the treatment of African sleeping sickness in 1922, it was one of the first anti-infective agents that had been developed in a medicinal chemistry program. Unfortunately, many, many people took the EUA covid shot(s) before the dangers became obvious, and we are now praying that the consequences for those who took what was falsely presented as a vaccine will not be as serious as many experts have been desperately trying to warn us. Are there any supplements or lifestyle factors we can utilize to emulate the effects that suramin has? Researcher Dr Robert Naviaux of the San Diego School of Medicine gave suramin, a drug first developed in 1916, to 10 autistic boys between the ages of five and 14, and noted transformative results.
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